Search results for "ISM [X-ray]"

showing 10 items of 1056 documents

The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2.

2015

The NG2 proteoglycan is characteristically expressed by oligodendrocyte progenitor cells (OPC) and also by aggressive brain tumours highly resistant to chemo- and radiation therapy. Oligodendrocyte-lineage cells are particularly sensitive to stress resulting in cell death in white matter after hypoxic or ischemic insults of premature infants and destruction of OPC in some types of Multiple Sclerosis lesions. Here we show that the NG2 proteoglycan binds OMI/HtrA2, a mitochondrial serine protease which is released from damaged mitochondria into the cytosol in response to stress. In the cytosol, OMI/HtrA2 initiates apoptosis by proteolytic degradation of anti-apoptotic factors. OPC in which NG…

lcsh:MedicineApoptosisdrug effects [Cytosol]HTRA2 protein humangenetics [RNA Small Interfering]genetics [Serine Endopeptidases]genetics [Glioblastoma]570 Life sciencespathology [Glioblastoma]MiceCytosolCerebellumpathology [Cerebellum]RNA Small Interferinglcsh:Sciencemetabolism [Antigens]Mice Knockoutchondroitin sulfate proteoglycan 4metabolism [Proteoglycans]Brain NeoplasmsSerine Endopeptidasesdrug effects [Mitochondria]metabolism [Cerebellum]High-Temperature Requirement A Serine Peptidase 2Mitochondriametabolism [Brain Neoplasms]Gene Expression Regulation Neoplasticpharmacology [Antibodies Neutralizing]genetics [Mitochondrial Proteins]Proteoglycans570 BiowissenschaftenResearch ArticleProtein BindingSignal Transductionpathology [Brain Neoplasms]Primary Cell Culturedrug effects [Cerebellum]drug effects [Apoptosis]metabolism [Mitochondrial Proteins]Mitochondrial Proteinsantagonists & inhibitors [Proteoglycans]pharmacology [Hydrogen Peroxide]genetics [Antigens]Cell Line Tumormetabolism [Serine Endopeptidases]AnimalsHumansddc:610metabolism [RNA Small Interfering]Antigenslcsh:RHtra2 protein mouseHydrogen Peroxidemetabolism [Mitochondria]Antibodies Neutralizinggenetics [Proteoglycans]genetics [Brain Neoplasms]Mice Inbred C57BLOxidative Stressnervous systemlcsh:Qmetabolism [Cytosol]Glioblastomametabolism [Glioblastoma]
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Kollokative Variation im deutschen und österreichischen Zivilgesetzbuch

2020

Jak wiadomo, język niemiecki jest językiem pluricentrycznym z narodowymi odmianami/centrami, który w obrębie języka prawa różni się także ze względu na obowiązujące w różnych krajach niemieckojęzycznych różne systemy prawa. Austriacki kodeks cywilny (ABGB), uchwalony w roku 1811, jest prawie o cały wiek starszy od swego odpowiednika w RFN (BGB), który wszedł w życie w roku 1900. Ów dystans czasowy pociąga za sobą także różnice w zakresie języka obu kodeksów. Celem artykułu jest pokazanie cech wspólnych i różnic w obrębie kolokacji w niemieckim i austriackim kodeksie cywilnym, które dotąd prawie całkowicie pozostawały poza obszarem badań.

legal linguisticsprawo cywilnekolokacjefrazeologia języków specjalistycznychcollocationscivil lawpluricentrism in the German languages of lawLSP phraseologylegilingwistykapluricentryzm niemieckiego języka prawaPrace Językoznawcze
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Il diritto penale oltre la frontiera

2023

A partire dalla considerazione del ruolo che il principio di territorialità riveste nel diritto penale, il contributo sviluppa una rapida riflessione sui rapporti tra cosmopolitismo giuridico e diritto penale e si interroga sui possibili influssi che le teorie sul fondamento universalistico dei diritti umani possono esercitare sul sistema penale stato-centrico.

legge penale nello spaziodiritto penale internazionale.Settore IUS/17 - Diritto PenaleStarting from the consideration of the role that the Territorial principle plays in criminal law the paper focuses on the relationship between legal cosmopolitanism and criminal law also with regard to the possible influence that theories on the universalistic foundation of human rights may have on the state-centric criminal system.cosmopolitismo penale
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Litorali dell'autofinzione: spigolature lacaniane

2017

Questo articolo intende applicare gli strumenti teorici della psicoanalisi lacaniana allo studio del romanzo autofinzionale. Si tratta, per un verso, di operare una lettura del romanzo "L'étreinte" di Philippe Vilain al livello del significante; per un altro, di cogliere le implicazioni del Simbolico in vari romanzi dello scrittore omosessuale marocchino Rachid O. L'articolo intende inoltre formulare una riflessione sul valore della critica letteraria per Jacques Lacan e sul come tale critica debba concepirsi nella logica dell'oltre-Edipo. This article aims to apply the theoretical tools of Lacanian psychoanalysis to the study of the self-fictional novel. On the one hand, it is a matter of …

literary criticism and psychoanalysiomosessualitàcritique littéraire et psychanalysepsicoanalisi lacanianaRomanzo autofinzionaleSelf-fictional novelcritica letteraria e psicoanalisiSettore L-LIN/03 - Letteratura FranceseRoman autofictionnelLacanian psychoanalysihomosexualityhomosexualitépsychanalyse lacanienne
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El análisis marxista de las necesidades sociales

2018

The disappearance of the so-called «real socialism» has concealed the validity of the Marxist analysis of social reality. One of the sets of hypotheses that has best maintained its heuristic capacity is the Marxist theory of needs. The Marxist hypotheses have been developed in debate with other conventional conceptions. Currently, feminism and the ecological analysis of needs are renewing the views of Heller and Habermas.

límites ecológicosLluísteoría críticaHellerColom Cañellasteoría feministaHell er:SOCIOLOGÍA [UNESCO]marxismofeminism and the ecological analysis of needs are renewing the views of Heller and Habermas. necesidades sociales1137-7038 8537 Arxius de sociologia 493757 2018 38 6508343 El análisis marxista de las necesidades sociales Ballester BrageHabermasMarxismUNESCO::SOCIOLOGÍAAntoni J. The disappearance of the so-called «real socialism» has concealed the validity of the Marxist analysis of social reality. One of the sets of hypotheses that has best maintained its heuristic capacity is the Marxist theory of needs. The Marxist hypotheses have been developed in debate with other conventional conceptions. CurrentlyCritical Theorysocial needsecological limitsFeminist Theory. 37 48
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Challenges in Marketing Communications During the COVID-19 Pandemic

2022

The purpose of this study is to explore how tourism and hospitality firms managed marketing communications (marcom) since the COVID-19 outbreak and to propose a conceptual framework on marcom challenges that the pandemic crisis has brought to the industry. In-depth interviews were conducted with tourism and hospitality managers in Croatia, a destination that registered remarkable tourism results in 2021. The proposed conceptual framework reflects the adaptation process and major changes in B2B and B2C communication since the COVID-19 outbreak on one hand and resulting strategic opportunities for marcom managers on the other, discussed in terms of practical implications. To the best of the a…

marketing communicationsqualitative methodTourism Leisure and Hospitality ManagementUNESCO::SOCIOLOGÍAGeography Planning and DevelopmentCOVID-19conceptual frameworkcrisis communicationtourism and hospitality managersmarketing communications; crisis communication; conceptual framework; qualitative method; tourism and hospitality managers; COVID-19Tourism
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Les stratégies de développement touristique des territoires de l’espace Rhin-Rhône : une nouvelle cohérence impulsée par le TGV

2012

International audience; The eastern branch of the Rhine-Rhône highspeed line was opened on 11th December 2011. It offers new connections in France and in Europe. Relationships between transport and economic development has often been studied in the literature. This article is an analysis of the relationship between transport, tourism and territory based on the promotion campaigns and the tourism development strategies in the territories newly connected by the high-speed line. Local projects have been catalogued and regional players have been interviewed in order to show how this new infrastructure can be appropriated to enhance the territorial reputation. An analysis of the current cooperat…

marketing territorial[SHS.GEO] Humanities and Social Sciences/GeographyTGV Rhine-RhôneTGV Rhin-Rhône[SHS.GEO]Humanities and Social Sciences/Geographydevelopment strategyterritorial marketingtourisme[ SHS.GEO ] Humanities and Social Sciences/Geographystratégies de valorisationtourism developmentComputingMilieux_MISCELLANEOUSTGVdéveloppement touristique
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Influence of odorant metabolism on human olfactory perception

2018

The sense of smell permits the perception of volatile substances commonly known as odors. This sense plays an important role in the feeding and wellness of individuals because it involves exchanges with their environment (search for food or partners, predators detection…). The efficiency of the olfactory system mainly relies on its sensitivity depending on the odorant affinity for their olfactory receptors but also on an enzymatic clearance mechanism of odorants which involves the Odorant metabolizing Enzymes (OME) to avoid the saturation of the receptors. Recent studies have shown that the biotransformation of odorants by EMO, in the olfactory epithelium, participates in the olfactory perc…

mebolism enzymes[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionvolatil organic compoundsanalytical biochemistrythesexenobiotic metabolismolfaction
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Medìakritika v sistemì žurnalìsts΄koї osvìtì Ykraїnì: L΄vìv – Kìїv- Tranzìt

2017

The article attempts to identify the place and significance of media criticism in the context of journalism education in Ukrainę. There is no ąuestion that criticism of the media has been around for nearly as long as the media themselves. As regards present-day curriculum courses in media criticism, they would be non-existent now without respective research, the results of which were first presented in scholarly and later on in educational materials. The author thus gives a brief overview of the theoretical background of the discipline in ąuestion before going on to discuss the place of media criticism in university curricula. He specifically touches on two books that contain number 100 in …

media criticismjournalism educationВісник Львівського університету. Серія Журналістика
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Exegesis and myths as methodologies of research in tourism

2013

Anthropology has given interesting paradigms to tourism-led research. From the role played by culture to the conflict between host and guest, anthropology has focused in mobility and tourism issues. Nonetheless, when we think in tourism we imagine an all-encompassing institution. There were many forms of tourism, each one enrooted in their own culture. Mythology and exegesis remind not only that other non-western forms of tourism are interesting to study but also how we can examine those cultural values that do not exist any longer. What this note of research sustains is that positivism monopolized in tourism fields some methods at the time pushing others to the periphery of knowledge, like…

media_common.quotation_subjectTourism geographyGeography Planning and DevelopmentEnvironmental ethicsMythologyInstitutionCultural valuesSociologySocial scienceExegesisPositivismTourismEarth-Surface Processesmedia_commonAnatolia
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